Smallest detectable difference (SDD)
Angst F, Aeschlimann A et al. Smallest detectable and minimal clinically important differences of rehabilitation intervention with their implications for required sample sizes using WOMAC and SF-36 quality of life measurement instruments in patients with osteoarthritis of the lower extremities. Arthritis Rheum 2001;45:384-91.
ES    n
0.80   25
0.50   63
0.20 395